Four infant deaths trigger vaccines halt
The health ministry has decided to suspend the use of two
types of publicly subsidized vaccines following the deaths of four children.
Municipal governments were notified of the decision.
The two types are the Hib vaccine, which prevents bacterial
meningitis, and a vaccine against streptococcus pneumonia.
There have been no reports so far from the doctors who
treated the children that there is a causal relationship between the vaccines
and the deaths, according to the Health, Labor and Welfare Ministry.
The ministry is planning to assemble a panel of experts this
week after consulting with other doctors to examine the cases, according to
The ministry is expected to let the vaccinations resume if
the panel decides the two vaccines don't pose serious safety concerns.
The four children were a 3-month-old girl in Kawasaki who
died Feb. 20, a 2-year-old boy in Takarazuka, Hyogo Prefecture, who died
Tuesday, a 1-year-old girl in Nishinomiya, also in Hyogo, who died Wednesday,
and a 6-month-old girl in the city of Kyoto who died Friday.
The doctors of the children described the causal relationship
between the vaccines and their deaths as either unclear or impossible to
evaluate. Some had underlying illnesses and others did not.
All four children were administered a vaccine against
streptococcus pneumonia made by Pfizer Inc., and all except the girl in
Nishinomiya received ActHIB, an Hib vaccine made by Sanofi Pasteur Inc.
In addition, all except the boy in Takarazuka received a
mixed vaccine against diphtheria, whooping cough and tetanus on the same day
they received other vaccines.
The streptococcus pneumonia vaccine has been administered to
an estimated 1.10 million people in 2.15 million doses since it went on sale
in February 2010. The Hib vaccine has been administered to an estimated 1.55
million people in 3.08 million doses since its launch in December 2008.
Japan, known for being notoriously slow to accept new
vaccines, approved the Hib vaccine in 2007, 20 years after the United States
did so. Approval for the streptococcus pneumonia vaccine came in 2009,
compared with 2000 in the U.S.
An increasing number of people are believed to be receiving
these vaccines because of a subsidy program launched last November in which
the government agrees to shoulder half the cost of vaccination if municipal
governments organize and subsidize vaccination programs.
Acute Encephalopathy Followed by Permanent Brain Injury or Death Associated
With Further Attenuated Measles Vaccines: A Review of Claims Submitted to the
National Vaccine Injury Compensation Program
Received Jul 30, 1997; accepted Sep 23, 1997.
Robert E. Weibel*, Vito Caserta*, David E. Benor
and Geoffrey Evans*
From the * Division of Vaccine Injury Compensation, National Vaccine
Injury Compensation Program, Health Resources and Services Administration,
Public Health Service, Rockville, Maryland; and the
Office of the General Counsel, United States Department of Health and Human
Services, Rockville, Maryland.
PEDIATRICS Vol. 101 No. 3 March 1998, pp. 383-387
Objective. To determine if there is evidence for a causal relationship
between acute encephalopathy followed by permanent brain injury or
death associated with the administration of further attenuated
measles vaccines (Attenuvax or Lirugen, Hoechst Marion Roussel,
Kansas City, MO), mumps vaccine (Mumpsvax, Merck and Co, Inc, West
Point, PA), or rubella vaccines (Meruvax or Meruvax II, Merck and Co,
Inc, West Point, PA), combined measles and rubella vaccine (M-R-Vax
or M-R-Vax II, Merck and Co, Inc, West Point, PA), or combined
measles, mumps, and rubella vaccine (M-M-R or M-M-R II, Merck and Co,
Inc, West Point, PA), the lead author reviewed claims submitted to
the National Vaccine Injury Compensation Program.
Methods. The medical records of children who met the inclusion criteria
of receiving the first dose of these vaccines between 1970 and 1993
and who developed such an encephalopathy with no determined cause
within 15 days were identified and analyzed.
Results. A total of 48 children, ages 10 to 49 months, met the
inclusion criteria after receiving measles vaccine, alone or in
combination. Eight children died, and the remainder had mental
regression and retardation, chronic seizures, motor and sensory
deficits, and movement disorders. The onset of neurologic signs or
symptoms occurred with a nonrandom, statistically significant
distribution of cases on days 8 and 9. No cases were identified after
the administration of monovalent mumps or rubella vaccine.
Conclusions. This clustering suggests that a causal relationship
between measles vaccine and encephalopathy may exist as a rare
complication of measles immunization.
Key words: measles vaccine, encephalopathy, encephalitis.
Comments are convincing. One especially:
November 6, 2009 at 11:00 am (40) kathy-sd says:
"I'm from a town of 2000 in SD, there are several women pregnant and we are all
due within a few weeks of each other. Four of us got the H1N1 vaccine 2 weeks
ago and one by one each of us started to have preterm contractions. We are all
due in Nov and Dec so we are further along than most of the people that lost
their babies. There is no way you can tell us that our preterm labor was not
caused by the H1N1 vaccine. It may look like a "fluke" to some people when these
women are scattered all over the country but we are talking about 4 of us in our
small community. My heart goes out to all of you that lost your babies."
Posted on Sun Nov 15 04:19:29 2009 by American Dream 246
The reports are rolling in:
(2) Regrets says:
I got both vaccines on Thursday. I was 9 weeks pregnant. I miscarried on Sunday.
I was told by several doctors to get these vaccines. Now I wish I followed my
gut feeling and not get them at ALL!
October 29, 2009 at 8:33 am (3) says:
i work in a hospital like setting and was told 'the benefits outweigh the risks"
1am i got the vaccine, 3am i started bleeding and craming, 3pm miscarried. you
October 31, 2009 at 1:29 pm (4) sue says:
I had the H1N1 vaccination and 24 hours later had a miscarriage.
October 31, 2009 at 8:25 pm (5) Linda Hill says:
My daughter in law was 10 weeks pregnant and had the H1N1 vaccine on Friday that
night she miscarried.
November 1, 2009 at 9:58 pm (6) Stephanie says:
I received the H1N1 over a week ago. I am now 5 weeks. I am doing well so far.
November 2, 2009 at 10:52 pm (7) SoSorry says:
I was so ready to get the H1N1 vaccine last week and they were only giving them
to pregnant women. I was 6 weeks along and got it and the next day I started
cramping and miscarried. I already had two healthy pregnancies and never
miscarried or had any problems. My doctors think I am crazy to think it was the
H1N1 but if no one looks into this than other women will not know. I am so sorry
that I got it.
November 3, 2009 at 4:30 pm (8) Connie says:
I also received the H1N1 vaccination on October 22nd, 2009 and went into labor
on October 25th, at 16 weeks pregnant and we just heard the heartbeat and
everything was fine with my pregnancy on October 16th, 2009, then on October
28th my water broke then on October 29th, I delivered a stillborn baby boy, and
no one can tell me why.Everyone wants to say it did not come from the shot but I
believe it did. My baby was growing at the correct pace and everyone wants to
brush off the vaccination. I say if you have the vaccination and suffer a
miscarriage if they are able to perform an autopsy have it done. November 3,
2009 at 4:34 pm
November 4, 2009 at 10:12 pm (10) sioux falls, south dakota says:
I received the H1N1 vaccine on October 16th and started experiencing cramping on
the 22nd. I was nearly 17 weeks pregnant and gave birth to a stillborn baby boy
on the 23rd. Like many of the other women here, the first thing I suspected was
the H1N1 vaccine. I immediately asked a nurse at the hospital if that would have
anything to do with it. Without hesitation, she told me "absolutely not." I had
reservations about getting the vaccine, but followed the advice of my long
trusted family doctor. In a follow up appointment with my doctor 3 days after I
lost my baby, I asked him if the vaccine would have had any adverse effects on
my baby. He also said that it was not possible. I don't believe that my doctor
was necessarily lying to me, he was simply following the accepted practices and
opinions of his field. I do, however, believe that as a nation, we are being
lied to. This vaccine is NOT safe during pregnancy. There has not been enough
testing done to determine this and there are far too many "coincidences" for
this to be anything but a result of a vaccine that was hastily pushed into
production and distribution in an effort to stop widespread panic. I have read
so many stories in defense of the vaccine that will talk about how common
miscarriages are, but I would challenge you to ask ANY health care professional
how common second trimester miscarriages are. My baby was doing perfect
developmentally and I had felt him move earlier that day. My heart goes out to
all of you out there who have had to go through the same heartache and loss that
I have had in the last couple of weeks. There is no reason that any woman or
family should have to go through this. Get the word out to all of the pregnant
women that you know. I know that if I had heard that women had been losing their
babies shortly after they received the vaccine, I would have followed my gut and
not gotten it myself. Maybe then Wyatt would have had a chance at life.
November 6, 2009 at 8:16 am (36) Marina Rossi says:
I recently got the H1N1 vaccine and miscarried 3 days later. I thought it could
have been the vaccine but didnt ask. After finding this site I believe it was
the vaccine. Sorry to everyone else out there who has just experienced a
November 6, 2009 at 11:54 am (42) ashley says:
Im not sure but not only myself, i know someone that withing 4 days of getting
the shot we both miscarried, i was only 6 weeks and she was 4 months along, not
sure if the shot caused it and cant find any other information but i am a little
concerned about this coincidence.
November 11, 2009 at 2:05 pm (238) zoe says:
I was vaccinated on Friday and on Tuesday my first trimester screening
ultrasound showed that my baby did not have a heart beat. I was 12 weeks along
and the baby measured 12 weeks so it must have happened after the vaccination
(when I was 11 weeks). I doubt that they will ever draw any conclusions about
the cause of my baby's death but it is quite uncommon to have a miscarriage
after 12 weeks and if I could make the decision again, I would have played it
safe (although that's what I thought I was doing) and NOT have had the shot.
Still thinking about getting a flu shot?
This is a heart breaking story from a friend of mine... Yes, tomorrow I will be
protesting (with the consent of the mother who I'm still waiting to hear back
from) in memory of Wyatt James Ihnen. The mother who received the vaccine is my
best friend's sister-in-law. I am extremely close to the family.
She went in to get the H1N1 shot and that same night started experiencing cramps
and the baby started kicking more than usual. She didn't think anything of it at
first, just thought that she was getting sick or something, but the next morning
she still had cramps so she went to the hospital and Wyatt was stillborn
(natural birth!). Wyatt was 17 weeks old and 7 inches long. The mother and child
were healthy with no complications prior to the shot.
She and the father are having an extremely hard time with the death of their
son. She feels like by baby Wyatt kicking he was trying to tell mommy," Help
me!" That thought haunts her.
The family performed a funeral and everything.
Dr. Joseph S Arvay Doctor of ChiropracTIC 303.457.8080 office 303.349.6011 cell
Emily November 14th, 2009 at 8:22 pm
THIS WEEK.. Tues 10 Nov 2:30pm I had the seasonal flu shot (not H1N1)- supposed
to be safe for pregnant women & highly advised. Wed 11 Nov 4:30pm began bleeding
and taken by ambulance to ER where heartbeat could not be confirmed externally.
Thurs 12 Nov 9:30am internal ultrasound confirmed no heartbeat. Fri 13 Nov I had
a D&C. My heart is absolutely broken.
I have never had a miscarriage before. Have 1 healthy son who I carried to term.
No history of poor health (ie: diabetes, obesity, blood pressure, etc.)No
drugs/alcohol. I eat a healthy diet with lots of raw veggies & fruit, but not
I heard my baby's heartbeat just a few weeks before and everything seemed to be
progressing normally. Now may baby is gone and there is nothing I or anyone can
do to turn back the clock. I will never know if this immunization was the cause
of my loss or what. But I am utterly broken. Emily, Ft Benning, GA, USA
11-08-2009, 09:26 PM nic.cox
This is so sad.
A friend of ours had a miscarriage on October 30th. She was just over 12 weeks
along, and there was no heartbeat at the 12 week ultrasound. She was right on
target for size and heartbeat the week before.
I just called my close friend (the woman who miscarried's best friend) and asked
if she had gotten the H1N1 shot recently. It turns out that she got the shot the
week before, at 11 weeks, when everything was fine with the pregnancy. Makes me
Personally, I'd never get a vaccine while pregnant. My gut just says "NO" and I
try to trust that instinct, as it hasn't led me wrong so far.
Charlotte Thomson Iserbyt
Former Senior Policy Advisor
U.S. Department of Education
VIC (Vaccine Information Coalition)
Autism is 1 in 67 children today and it's impossible to have a genetic epidemic!
Please learn from our mistake and educate BEFORE you vaccinate!
For more information visit www.vacinfo.org or call 800-939-8227
Dutch pull Pfizer infant vaccine after deaths
November 6, 2009 — 7:42am ET | By Liz Jones
Dutch health authorities have yanked a batch of Pfizer's Prevnar following the
deaths of three infants.
Prevnar, which is known as Prevenar in Europe, is used to protect infants from
certain pneumococcal bacteria that can cause meningitis and bacteremia. Pfizer
acquired the drug through its recent acquisition of Wyeth.
"On average about 5 to 10 deaths are reported annually after babies get
vaccines," said a spokeswoman for the Dutch health institute RIVM. Each infant
had received the vaccine within the past two weeks, according to Forbes.
Pfizer spokeswoman Gwen Fisher said preliminary investigations by the company
and health authorities had found no link between the vaccinations and the
deaths. Fisher said the company initiated the "quarantine" of the batch, which
she said contained 110,000 doses of the vaccine. She added that the three
infants also received two unrelated other vaccines as part of routine
Read more: http://www.fiercepharma.com/story/dutch-pull-pfizer-infant-vaccine-after-deaths/2009-11-05#ixzz0YfHbdQGQ
With trembling hands, the distraught mother stroked the yellow bear which
belonged to Finlay – her beloved son. The little boy died two weeks ago at the
age of 21 months after having a vaccination against swine flu.
Mother Yvonne B. (34), a nurse for the elderly in Berlin, said: “Finlay was born
with a heart defect and damaged lungs. He had been operated on four times. Now
he was waiting in hospital for a new heart and a new lung. “He was doing quite
well. We went out with him everyday. He played in the leaves and liked to watch
Doctors told the parents that the tot should be inoculated, mirroring the advice
of the standing committee on vaccinations.Mom-of-three Yvonne added: “They said
the side effects would be no problem, but that swine flu would be a real danger
to our son. On top of that, a patient in the room next door had been diagnosed
with swine flu.”
In the afternoon the boy was vaccinated. On the next day he was still laughing
and happily playing around in the leaves. But in the night, his condition
suddenly worsened. He vomited and fluid got into his lung. The organ failed, and
then so did his heart. The devastated mother said: “We were called at night.
Finlay fell asleep on my husband’s arm.” Immediately a horrific thought surfaced
- was the H1N1 virus vaccination to blame for the agonising tragedy? “The
assumption is simply an obvious one! At least that the vaccination played some
kind of role.”
The parents consented to an autopsy of their son. “The Pathological Institute
told us yesterday they couldn't exclude a connection, but also that there was
nothing speaking for it compellingly. “If I had the choice again, I would not
let my son be vaccinated.” The investigation of the boy’s death is still
ongoing. A week ago the parents carried their son to his grave. “He had an
unbelievable willingness to live. We never thought for a second that he wouldn’t
make it,” said his mother.
“The name Finlay means ‘small blond hero’. We had so much hope that our little
hero would finally be able to start living.”
after getting Chinese H1N1 vaccine
PTI | Beijing
Two people have died in China after receiving domestically manufactured vaccines
against swine flu, Government said on Saturday.
The preliminary autopsy report of one of the deceased showed that the patient
suffered a sudden cardiac death while results of the autopsy on the second
person are still awaited, the Ministry of Health was quoted as saying by the
Xinhua news agency.
“Experts have basically ruled out the possibility that the patient’s sudden
death was the result of immediate allergic reactions to the flu vaccines,” a
statement on Ministry’s Website said.
Around 43 people have so far succumbed to swine flu in China due to the disease.
GlaxoSmithKline H1N1 Vaccine Disaster Toll Rises
There have been 24 confirmed cases of a type of severe allergic reaction called
anaphylaxis in Canadians who have received an H1N1 flu shot, including one
person who died after getting vaccinated, the head of the Public Health Agency
of Canada said Wednesday. Butler-Jones disclosed the information in Ottawa
during a news conference at which federal health officials revealed flu activity
appears to be levelling off. All but 15,000 doses of the vaccine had been used
by the time the halt-use order was issued, said Dr. Danielle Grondin, assistant
deputy minister of the public health agency. But confirmed cases of anaphylaxis
have been seen with other batches as well. And some possible cases may still be
Helen Branswell, Medical Reporter, Canadian Press
Baby dies after
“Exact cause of death can be ascertained only after visceral analysis is
Krishnagiri: A two-month old female baby died reportedly after being given
Diptheria-Pertussis-Tetanus (DPT) and Hepatitis B vaccination shots at
Kappalvadi near Bargur on Wednesday.
According to sources, the baby developed fever 11 hours after being
administered the vaccines at the Kappalvadi Primary Health Centre. The parents gave tablets as prescribed by a doctor at the PHC. Though the
temperature came down initially, it shot up again. The baby developed diarrhoea
and the parents rushed the child to a private hospital in Bargur. Doctors on
duty referred the baby to the Krishnagiri Government Hospital. However, it died
on way to the hospital.
K. Ganesan, Deputy Director, Health Services, ruled out the possibility of
allergic reaction due to immunisation. The vaccination was administered after
taking all precautions, he said. The exact cause of the death could be ascertained only after the visceral
analysis was done at the Salem Government Medical College Hospital.
More than 22 children were given vaccine shots at the Kappalvadi PHC on the
day of the immunisation campaign and no complaint was received from any of the
Over 90 hospitalized after measles vaccination in east Ukraine
12:40 | 18/ 05/ 2008
KIEV, May 18 (RIA Novosti) - A total of 92 people, including 87 children, were
hospitalized in eastern Ukraine as of early Sunday after measles vaccination,
Ukraine's emergencies ministry said.
On May 13, a 17-year-old boy died after measles inoculation in the Donetsk
Region. Two days later, over 60 people in eastern Ukraine were hospitalized
after vaccination. A total of over 20,000 people in the region received the same
Ukraine's President Viktor Yushchenko said he was concerned over the teenager's
death and demanded from the Ukrainian health ministry to take all measures to
prevent such instances in the future.
By now, measles immunization has been halted in Ukraine.
Hepatitis-B vaccine suspended nation-wide
Ha Noi — The Ministry of Health has given orders to ban further use of two
batches of hepatitis-B vaccine nationwide as they wait for autopsy results on
two children who died following vaccination. Deputy Health Minister Cao Minh
Quang made the announcement yesterday to suspend the two batches of hepatitis-B
vaccine produced locally by the Biological Product and Vaccine Company 1.
The two children were one-week-old Nguyen Ngoc Thao from Hoa Binh Province who
died on June 4 after being injected with hepatitis-B and tuberculosis vaccines
at the province’s Cham Mat health clinic. Some days earlier, on May 25,
four-month-old Nguyen Ba Thanh from Ha Tay Province also died after receiving an
injection of hepatitis-B vaccine and DPT vaccine against diphtheria, pertussis
and tetanus; and an oral polio vaccine.
HCMC suspends US-made vaccine after worker’s death
Last Updated: Saturday, June 9, 2007 13:34:26 Vietnam (GMT+07)
The Ho Chi Minh City Health Department has ordered city hospitals and health
centers to stop using a batch of US-made vaccines after a worker died and five
others fell ill after getting vaccinated.
Six women workers from the Tango Candy Company were hospitalized Tuesday 30
minutes after getting a shot of MMR, a vaccine to protect people against
measles, mumps, and rubella (German measles).
One worker, Huynh Thi Kim Hoa, experienced breathing difficulties and a fall in
heart rate, and she later fainted and slipped into a coma. Hoa was taken to Gia
Dinh Hospital where doctors said she had suffered a brain hemorrhage.
The 20-year-old died Friday morning.
Hospital director Do Hoang Giao said Hoa's condition was not caused by the
vaccination but was the result of defective blood vessels around her brain. The
bleeding could have been triggered anytime.
The five others also suffered breathing difficulties and were also taken to the
hospital. Doctors discharged them that evening.
The batch in question, H1666, was manufactured by American drug company Merck
Sharp & Dohme Inc. on October 24, 2004, and expires in November this year.
The city Preventive Health Center said it imported 10,000 doses of the vaccine,
more than 1,000 of which had already been used.
Source: Tuoi Tre, Lao Dong, VietNamNet – Translated by Thu Thuy
Thursday, April 24, 2008 (Chennai)
The measles immunisation programme across Tamil Nadu has now been put on hold
and two nurses have been suspended after four babies died soon after getting
vaccinated for measles. The Union Health Ministry has rushed a two-member team
of experts to the area. Samples of the vaccine have been sent for testing. There
are also reports that the medical camps did not have any provisions for
A mother, Arputhamaal, who was blessed with a girl baby twenty years after her
marriage, lost her child to the killer vaccine. The ten-month-old died on
Wednesday soon after she was administered measles vaccine, in the Thiruvallur
district of Tamil Nadu. Three other babies too lost their lives after
vaccination at their neighbourhood government health centre. Arputhamaal was
inconsolable and visibly shaken after she lost her child. ''I had not taken my
daughter to the hospital even once after the birth. And the first time she was
taken she died, said Arputhamaal, a mother.
Another mother recounts the horror she faced at the immunization center.
''She died at the centre itself soon after the vaccine. Froth started coming out
of her nose instantly,'' said Suganthy. The state government has ordered a
probe. According to the health officials, the vaccine was supplied by the
Central government-owned Human Biological Institute in Hyderabad. There's a pal
of gloom along with simmering tension in the area. While the government has
announced a compensation of Rs three lakh to families, there is no consolation
for those who have lost their innocent children. Ironically, Tamil Nadu is in
the forefront of the vaccination movement in the country. The state has
successfully eradicated polio and several other diseases.
In January 2008, Tamil Nadu became the first state chosen for implementing the
Hepatitis-B vaccination programme.
Second child dies from the flu
March 14, 2008
St. Paul, Minn. — Minnesota has recorded its second
pediatric influenza-related death this season. The Minnesota Department of
Health says a 5-year-old girl from the greater Twin Cities metro area died
this week shortly after receiving a flu shot. Immunizations expert Kris Ehresmann said the girl received
her flu vaccination on March 4th.
"She was healthy. She didn't have any underlying health
conditions and had a history of being vaccinated," Ehresmann said. "Although
she was vaccinated while she was already ill and infected. So likely that
obviously didn't provide any protection." The child who died earlier was a 12-year-old who hadn't
Ehresmann said flu shots are still available. The flu
season typically runs through the end of April.
Another baby dies, hepatitis shot blamed
27 Apr 2008, 0238 hrs IST,TNN
DINDIGUL: Tension gripped Dindigul after parents of an 11-month-old girl baby,
Mariammal, blamed the hepatitis B vaccine for her death on Saturday. Mariammal
was administered the vaccine two days ago at the Narasingapuram primary health
centre in the district. She died on Saturday morning at the Dindigul Government
Deputy Director of Health, Dr. K Jagadeesh Kumar, however, dismissed the claims
of Murugesan and his wife Nagammal that their baby had died of the vaccine. "The
preliminary report says the baby died of aspiration asphyxia. She was severely
malnourished and terribly underweight when she was brought to the PHCs."
Mariammal’s parents complained that she developed high fever and when they took
her to the Government Hospital there was no doctor to take care of her.
With four babies in Tiruvallur district dying after being administered the
measles vaccine on Wednesday, a wave of panic has spread across the state, with
at least two more districts, including Dharmapuri and now Dindigul, reporting
deaths of babies due to vaccines.
Several cadres of the CPM and SFI staged a demonstration in front of the
hospital, demanding action against the vaccine manufacturers.
On Thursday, a 3 month-old boy died in Dharmapuri district, 10 days after he was
given triple antigen shots.
Human error or faulty measles vaccine? One Of These Reasons Killed Four Babies
In Tamil Nadu, Finds The Initial Probe Kounteya Sinha
NewDelhi: All four children who died after being administered the measles
vaccine in Tamil Nadu on April 23 suffered severe brain haemorrhage resulting
from an anaphylactic shock, an inquiry has found. This will be pointed out by
the five member expert team sent by the health ministry to investigate the
deaths, when they submit their initial report to health minister A Ramadoss on
Monday. Experts in the team said an anaphylactic shock—a severe, potentially
lethal systemic allergic reaction—following a measles vaccination is highly rare
and occurs in one out of every 10 lakh cases. They said the anaphylactic shock
killing all four—within half-an-hour of the vaccine being administered around
the same area—pointed to two likely reasons for why the deaths occurred—a human
error resulting in mixing thef reeze-dried vaccine with a different chemical in
place of saline water or a contaminated vaccine containing a foreign protein,
like bacteria, from being kept in the open for more than three hours after being
Ateam member who returned from Chennai on Friday after investigations ,however,
confirmed that the public health centre’s cold chain system, which was used to
store the vaccines, was not at fault. Puttingto rest allegations that the nurses
may have used the same syringe to vaccinate the three children after dipping it
in chemicals like adrenaline or muscle relaxants, the team said individual
syringes were used. One of the experts said, “There was no conflict between what
the nurses, angadwadi workers and family members of children who died said. The
cold chain system was fine. Police reports also showed that individual syringes
were used. But the government hospital which carried out the postmortem found
that all of them died of haemorrhage, which is strange.” The Central Drug
Laboratory has started testing 20 samples of the vaccine from the same batch
that killed the children—10 each collected from the fatal site in Tiruvallur and
those lying with the Human Biologicals Institute in Hyderabad. Worried about its
good manufacturing standards, the health ministry is nowsending a three-member
team to HBI on Tuesday to check the PSU’s measles vaccine production unit.
“HBI is a pre-qualified WHOunit. However, we need to be sure that it is
following goodmanufacturing standards set by WHO and the government of India.
Theteam will inspect the vaccine production area, check raw materialsbeing used
and inspect its quality control measures,” a health ministry official said.
He added, “This case is really intriguing. Asingle child can be sensitive to the
vaccine and suffer from ananaphylactic shock. But how can it occur on three
children, one afteranother, after being administered the vaccine from a single
vial? On the other hand, records show that 230 doses of the same vaccine
batchwere used in the same PHC that day but no other deaths were recorded.”
The team of experts has said that the public health centre’s cold chain was not
to blame for her grief
12 Babies die during vaccine trials in Argentina
Buenos Aires, Jul 10, 2008 (Buenos Aires, Jul 10, 2008
At least 12 babies who were part of a clinical study to test the effectiveness
of a vaccine against pneumonia have died over the past year in Argentina, the
local press reported Thursday. The study was sponsored by global drug giant
GlaxoSmithKline and uses children from poor families, who are "pressured and
signing consent forms," the Argentine Federation of Health Professionals, or
Fesprosa, said. "This occurs without any type of state control" and "does not
with minimum ethical requirements," Fesprosa said. The vaccine trial is
still ongoing despite the denunciations, and those in charge of the study were
cited by the Critica newspaper as saying that the procedures are being carried
out in a lawful manner.
Colombian and Panama were also chosen by GSK as staging grounds for trials of
the vaccine against the pneumococcal bacteria. Since 2007, 15,000 children under
the age of one from the Argentine provinces of Mendoza, San Juan and Santiago
del Estero have been included in the research protocol, a statement of what the
study is trying to achieve. "Only 12 have died throughout the country, which is
a very low figure if we compare it with the deaths produced by respiratory
illnesses caused by the pneumococcal bacteria," pediatrician Enrique Smith, one
of the lead investigators, said. In Santiago del Estero, one of the country's
poorest provinces, the trials were authorized when Enrique's brother, Juan
Carlos Smith, was provincial health minister. According to pediatrician Ana
Maria Marchese, who works at the children's hospital in the provincial capital
where the studies are being conducted, "because they can't experiment in Europe
or the United States, they come to do it in third-world countries."
"A lot of people want to leave the protocol but aren't allowed; they force
them to continue under the threat that if they leave they won't receive any
other vaccine," said Julieta Ovejero, great aunt of one of the six babies who
died in Santiago del Estero. Fesprosa's Juan Carlos Palomares said that "in most
cases these are
underprivileged individuals, many of them unable to read or write, who are
pressured into including their children" in the trials. According to Fesprosa,
"the laboratory pays $8,000 for each child included in the study, but none (of
that money) remains in the province that lends the public facilities and the
health personnel for the private research." EFE
The Times of India -Breaking news, views. reviews, cricket from across India
Baby boy dies after DPT vaccination
8 Aug 2008, 0907 hrs IST,TNN
SRIKAKULAM: A two-month-old baby boy died within 10 hours of being administered
a shot of DPT vaccine at a medical camp in Srikakulam district on Wednesday.
The boy, Savara Praveen, died at his home in Savara Jhoudupally of the
Maoist-infested Meliaput mandal, about 175 km from the district headquarters, on
the Orissa border. The infant was among 15 others who were given a DPT shot on
Wednesday morning. But sources said the boy was given hepatitis-B vaccine along
with the DPT shot.
Family members said Praveen started frothing at the mouth, turned blue and died
around 5.30 pm. Sources said Praveen, who was born on June 2, was administered
the vaccination by a health worker of Asha. The boy's parents -- Savara Janu and
Annapoorna -- are farm labourers belonging to the tribal community.
The child was doing well for the first few hours after the vaccination, but
cried a lot in the afternoon, and by evening, he died. What worsened the matter
was that there was no provision to take the baby boy to a nearby hospital. "We
did not plan for an ambulance or medical support," a health official said,
adding that it was supposed to be a routine programme of immunisation where
nearly 10,000 kids were given the DPT shots.
District immunisation officer Y Nagaraj rushed to the village and seized the
samples from various batches of the vaccine. "The vials of the vaccine have been
sent to Hyderabad for testing," he said. He said the boy was suffering from
aspiratory pneumonia and milk was flowing from his nose when a paediatrician
went to check him
The officials could not indicate whether the death was vaccine-related as the
parents refused to send the body for a post-mortem to verify the cause of death.
DM&HO Rambhatnaik said the boy was forcibly fed milk when he was crying.
"Parents could not react properly to the symptoms," he said. Praveen's death was
the first vaccine-related tragedy in eight years in the district.
Copyright © 2007 European Federation of Internal Medicine
Published by Elsevier B.V.
Status epilepticus and lymphocytic pneumonitis following
hepatitis B vaccination
Jozélio Freire de Carvalhoa, b and Yehuda Shoenfeldb, c, ,
aRheumatology Division, São Paulo University School of
Medicine, São Paulo, Brazil bDepartment of Medicine B, Center for Autoimmune
Diseases, affiliated to Tel-Aviv University Sackler Faculty of Medicine, Sheba
Medical Center, Tel-Hashomer, Israel cIncumbent of the Laura Schwarz-Kipp Chair
for Research of Autoimmune Diseases, Tel-Aviv University, Israel
Received 23 April 2007; revised 3 July 2007; accepted 22
October 2007. Available online 4 December 2007.
The case reported refers to a patient who developed status
epilepticus in the day of her third dose of hepatitis B vaccination and we
review the literature on this subject. A 12 year-old girl, without a relevant
previous history, taking no drugs, developed a seizure attack followed by
unconsciousness, and eventually died after three days of her third dose of
hepatitis B (HB) vaccination. Autopsy study revealed cerebral edema with
congestion and herniation and diffuse interstitial type pneumonitis. There seem
to be a straight forward time relationship between the third HB vaccine, the
event of convulsion and the sudden death of the patient. We suggest that, in
some cases, vaccination may be the triggering factor for autoimmune and
neurological disturbances in genetically predisposed individuals and physicians
should be aware of this possible association.
Keywords: Hepatitis B vaccination; Status epilepticus;
Vaccination; Vaccine; Convulsion; Pneumonitis
George Fisher who died aged 17 months, 10 days after having
the MMR triple jab.
A healthy baby boy who was heard "chatting away on the baby monitor" just hours
before he died received an MMR jab shortly after suffering a fever fit that the
vaccine may have aggravated, an inquest heard today.
George Fisher, who was 18 months old when he was discovered dead in his cot in
Cheltenham, Gloucestershire by his mother, Sarah Fisher, had been given the MMR
jab 10 days earlier in January 2006, a coroner heard.
George suffered from febrile convulsions, fits caused by high temperatures.
Fisher, 44, and her husband, Christopher, 43, believe the vaccine was
"implicated" in their son's death.
They say the temperature-raising effects of the drug on children with febrile
convulsions were not explained to them, and that this knowledge might have
allowed them to act sooner.
According to Department of Health guidelines, the jab should be given ''with
caution''. However, the guidelines do not ban child sufferers of febrile
convulsions from receiving it, but rather recommends monitoring their
Two doctors confirmed that giving MMR to sufferers such as George was permitted
under patient guidelines, with careful watches recommended.
In evidence, Fisher said her son had been a "healthy and robust" child who she
had breastfed for 11 months - longer than her other three children.
He was given antibiotics for his febrile illness shortly before he received his
MMR jab, and had been "running around playing football with his father" on the
Wednesday before he died .The night before he died, he was "chatting away on the baby monitor", she added.
"He took his bottle of water and I put the quilt over him, stroked his head and
said goodnight. I went to bed, heard him drink his water, then throw the bottle
on the floor. I heard him shuffling around."
At 8am, his sister Meg, who was sharing a room with him, called out to her.
"I was surprised he was not awake. I tried to wake him, but it was clear he was
dead because of his colour, and he was cold," Fisher said.
He had been due to attend a doctor's appointment for his worsening symptoms on
the day he died.
She added that she now knew George should have been more closely monitored
because of his previous condition.
The coroner heard George was born at a healthy 8lbs 10oz, and came through his
routine injection with no side-effects.
Dr Annette Bugaighis, his GP, said the child fell ill on September 25, 2005,
after returning from a holiday in Spain, and developed a high temperature.
After suffering a fit at the Overton Park surgery, he was rushed to hospital,
where it was found he had suffered febrile convulsion. When admitted, George had
a high temperature, stiff neck, puffy eyes, and green-tinged stools.
Both Dr Annette Bugaighis and consultant paediatrician Alan Day of Cheltenham
general hospital agreed that he was safe to be given the vaccine on January 9
2006, and that he should be monitored for raised temperature.
"There was nothing obvious in his medical history to explain his sudden death,''
Dr Bugaighis said.
A Department of Health pamphlet advises only that MMR2 should be given "with
caution" to those "with an individual or family history of cerebral injury or
any other condition in which stress due to fever should be avoided. The
physician should be alert to the rise in temperature that may follow."
Mr Fisher said that the family had not been given a patient information leaflet
on the MMR precautions to be taken with children who had previously suffered
fever. Nor was any verbal advice specific to his circumstances.
"How I remember it, we were told if he had a rising temperature to give him
Calpol if he got grizzly. I had been present at all my children's vaccines and
it's the same spiel on every occasion," he said.
"Given his condition, they should have been aware of his medical history. At no
point were we asked for this before his vaccination."
"If we had been [given the leaflet], we would have gone to hospital much quicker
because of the information in that list. We would have been much more concerned
than we actually were."
Heather Mitchell, the nurse who gave George his injection, said she trusted his
parents' instincts and was satisfied when they told her George was well on the
Nurse Mitchell, who vaccinates "in excess" of 1,000 babies a year, said no
specific advice was required other then regular checking of temperature.
The Gloucestershire coroner, Alan Crickmore, will hear up to three days of
evidence at the Shire Hall, Gloucester, before recording a verdict.
Ten years ago, research led by Dr Andrew Wakefield, a gastroenterologist at
London's Royal Free Hospital, prompted fears that the combined Measles, Mumps
and Rubella vaccine was linked to autism.
Despite several studies in Britain, Finland and Japan disproving the connection,
anxiety has persisted over the vaccine. Cases of measles have topped 1,000 for
the first time in more than a decade, according to information that emerged last
week. The Health Protection Agency has attributed the rise to the "relatively
low" uptake of the MMR vaccine.
Ukrainian Teenager's Death
Blamed on Illegal Vaccine
Wednesday, May 27, 2009
KIEV, Ukraine — Ukrainian prosecutors have ordered a senior health official
detained on suspicion of illegally importing millions of doses of a vaccine that
they charge caused a teenager's death, officials said Wednesday.
United Nations agencies have concluded that
the 17-year-old boy's death in May 2008 was caused by a bacterial infection
unrelated to the U.N.-certified vaccine for measles and rubella he had just
received. But his death still led to widespread fears over immunization and
caused health officials to terminate a campaign to revaccinate 9 million
Ukrainians for measles and rubella.
Dr. Fedir Lapiy, an expert in infectious
diseases based in Kiev, has said that the Ukrainian government, plagued by
infighting between various political groups, has mismanaged the crisis. Lapiy
says that some officials have used the investigation to discredit their
political opponents instead of conducting a thorough probe.
Prosecutors have accused former Deputy
Health Minister Mykola Prodanchuk of importing the vaccine without properly
registering it here, which they say eventually led to the boy's death. They have
provided no details on how the vaccine is alleged to have killed the boy.
Yuriy Boychenko, spokesman for the
Prosecutor General's office, told The Associated Press Wednesday that a Kiev
court issued a search warrant for Prodanchuk after he failed to show up for
questioning. Prodanchuk must be detained while a court decides whether he should
be held in custody pending the investigation, Boychenko said.
Prodanchuk, who resigned shortly after the
teenager's death, has maintained his innocence. His lawyer, Mykola Shupenya,
told the AP that he was in a hospital with an unspecified lung condition and
could not appear in court. UNICEF, the U.N. children's agency, declined to
comment. The World Health Organization reiterated that officials believe the
vaccine was not responsible for the boy's death. Experts say termination of the
vaccination campaign and the widespread refusals of vaccination could lead to
major disease outbreaks in this France-sized country of 46 million and
potentially spread to its European neighbors.
China's Ministry of Health on Thursday ordered a probe into
unsafe vaccines after a media report claimed they had caused the death of four
children in the northern Shanxi province.
On Wednesday, the China Economic Times in an
investigative report claimed that faulty vaccines sold by the local government
between 2006 and 2008 led to the deaths of at least four children and left at
least 74 sick. The paper blamed health authorities in Shanxi of storing the
vaccines improperly and alleged that local officials had allowed an unqualified
company to make the vaccines. Some officials were involved with the company,
said the report. Four children aged between eight months and three years had
died after being vaccinated, while others had developed encephalitis.
The health bureau of the Shanxi provincial government rejected
the report, though the Ministry of Health in Beijing said the claims would be
fully investigated. The Ministry said in a statement it had “immediately begun
an investigation and demanded the Shanxi health authorities report as soon as
possible any new abnormal reactions to the vaccines”. If accurate, this will
only be the latest in a series of food and drug safety scandals here that have
stoked public ire against the government; most evident in 2008 when tainted milk
left more than 3,00,000 children ill.
Wary of the spread of public anger, authorities on Thursday
moved quickly to restrict local newspapers in Shanxi from reporting on the
deaths. The Internet Propaganda Administrative Bureau had ordered the deletion
of all references to reports on the vaccines, said the International Federation
of Journalists (IFJ) in a statement.
Even when the tainted milk scandal broke in 2008, one month
before the Beijing Olympics, local newspapers were barred from reporting on
children falling ill for more than two months. Chinese journalists had
discovered in July 2008 that several provincial hospitals were reporting a large
number of babies becoming sick after consuming milk powder made by Sanlu, one of
the country's biggest dairy companies. A subsequent investigation found that
milk sold by at least 22 Chinese brands contained the industrial chemical
melamine, which appears to raise the appearance but not actual level of protein
in dairy products.
The government acknowledged the milk scandal only in September,
after the Olympics had concluded. By then, more than 3,00,000 babies and young
children had fallen ill and six had died.